Welch Medical Library Guides: Finding Datasets for Secondary Analysis: NIH Data Repositories

NIH Data Repositories

In general, NIH does not endorse or require sharing in any specific repository and encourages researchers to select the repository that is most appropriate for their data type and discipline (though such specification does exist for particular initiatives). To help researchers locate an appropriate resource for sharing their data, as well as to promote awareness of resources where datasets can be located for reuse, Trans_NIH BioMedical Informatics Coordinating Committee (BMIC) maintains lists of several types of data sharing resources:

Open NIH-supported domain-specific repositories that house data of a specific type or related to a specific discipline;
Other NIH-supported domain-specific resources, including repositories and knowledgebases, that have limitations on submitting and/or accessing data; and
Generalist repositories that house data regardless of type, format, content, or subject matter.

Examples of NIH Data Repositories

Biologic Specimen and Data Repository Information Coordinating Center (BioLINCC)
The goal of BioLINCC is to facilitate and coordinate the existing activities of the NHLBI Biorepository and the Data Repository and to expand their scope and usability to the scientific community through a single web-based user interface.
Data and Specimen Hub (DASH)
NICHD DASH is a centralized resource for researchers to store and access de-identified data from NICHD funded research studies for the purposes of secondary research use. It serves as a mechanism for NICHD-funded extramural and intramural investigators to share research data from studies in accordance with the NIH Data Sharing Policy and the NIH Genomic Data Sharing Policy.
EyeGENE® (NEI)
The eyeGENE® Biorepository and corresponding Database contain family history and clinical eye exam data from subjects enrolled in eyeGENE® Program coupled to clinical grade DNA samples. This data and samples are submitted by collaborators throughout the US and Canada and the data is available on a controlled access basis to researchers world-wide.
Inter-University Consortium for Political and Social Research (ICPSR)
An international consortium of more than 750 academic institutions and research organizations, ICPSR provides leadership and training in data access, curation, and methods of analysis for the social science research community. ICPSR maintains a data archive of more than 250,000 files of research in the social and behavioral sciences. It hosts 21 specialized collections of data in education, aging, criminal justice, substance abuse, terrorism, and other fields.
The National Institute on Aging Genetics of Alzheimer’s Disease Data Storage Site (NIAGADS)
The National Institute on Aging Genetics of Alzheimer's Disease Data Storage Site (NIAGADS) is a national genetics data repository facilitating access to genotypic and phenotypic data for Alzheimer's disease (AD). Data include GWAS, whole genome (WGS) and whole exome (WES), expression, RNA Seq, and CHIP Seq analyses.
OpenfMRI
The OpenfMRI database is a curated public repository of human and non-human brain imaging data collected using MRI technique (potentially with additional PET, EEG and MEG data). No registration or license agreement is required to obtain the data, which is distributed, by default, using a Public Domain license.